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WormBase: A Cross-species database for comparative genomics
Harris TW1, Lee R2, Schwarz E2, Bradnam K3, Lawson D3, Chen W2, Blasier D4, Kenny E2, Cunnigham F1, Kishore R2, Chan J2, Muller HM2, Petcherski A2, Thorisson G1, Day A1, Bieri T4, Rogers A3, Chen C3, Spieth J4, Sternberg P2, Durbin R3, and LD Stein1
2003. Nucleic Acids Res.. 31: 133-137.
1 Cold Spring Harbor Laboratory, Cold Spring Harbor NY 11790, USA
2 Howard Hughes Medical Institute and California Institute of Technology, Pasadena, CA, USA
3 The Sanger Centre, Hinxton, UK
4 Genome Sequencing Center, Washington University, St. Louis, MO, USA
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WormBase (http://www.wormbase.org/) is a web-accessible central data repository for information about Caenorhabditis elegans and related nematodes. The past two years have seen a significant expansion in the biological scope of WormBase, including the integration of large-scale, genome-wide data sets, the inclusion of genome sequence and gene predictions from related species, and active literature curation. This expansion of data has also driven the development and refinement of user interfaces and operability, including a new Genome Browser, new searches and facilities for data access, and the inclusion of extensive documentation. These advances have expanded WormBase beyond the obvious target audience of C. elegans researchers, to include researchers wishing to explore problems in functional and comparative genomics within the context of a powerful genetic system.