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WormBase: a Comprehensive Data Resource for Caenorhabditis Biology and Genomics
Chen N1 , Harris TW1 , Antoshechkin I2 , Bastiani C2 , Bieri T3 , Blasiar D3 , Bradnam K4 , Chan J2 , Chen CK4 , Chen WJ2 , Davis P3 , Kenny E2 , Kishore R2 , Lawson D4 , Lee R2 , Nakamura C2 , Ozersky P3 , Petcherski A2 , Rogers A4 , Sabo A2 , Schwarz EM2 , VanAuken K2 , Wang Q2 , Durbin R4 , Spieth J3 , Sternberg P2 , and Stein LD1
1 Cold Spring Harbor Laboratory, Cold Spring Harbor NY 11790, USA
2 Howard Hughes Medical Institute and California Institute of Technology, Pasadena, CA, USA
3 Genome Sequencing Center, Washington University, St. Louis, MO, USA
4 The Welcome Trust Sanger Institute, Hinxton, UK
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WormBase (http://www.wormbase.org/), the model organism database for information about Caenorhabditis elegans and related nematodes, continues to expand in breadth and depth. Over the past year, WormBase has added multiple large-scale datasets including SAGE, interactome, 3-D protein structure datasets, and NCBI KOGs in addition to an extensive intellectual lineage of the C. elegans research community. To accommodate this growth, the International WormBase Consortium has improved the user interface by adding new features to aid in navigation, visualization of large-scale data sets, advanced searching, and data mining. Internally we have restructured the database models to rationalize the representation of genes and to prepare the system to accept the genome sequences of three additional Caenorhabditis species over the coming year.